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References 1. Wisgerhof HC, Edelbroek JR, de Fijter JW, et al. Subsequent squamous- and basal-cell carcinomas in kidney-transplant recipients after the first skin cancer: cumulative incidence and risk factors. Transplantation 2010; 89: 1231-8. 2. Hartevelt MM, Bouwes Bavinck JN, Kootte AM, Vermeer BJ, Vandenbroucke JP. Incidence of skin cancer after renal transplantation in The Netherlands. Transplantation 1990; 49: 506-9. 3. Hertog SA de, Wensveen CA, Bastiaens MT, et al. Relation between smoking and skin cancer. J Clin Oncol 2001; 19: 231-8. 4. Bouwes Bavinck JN, Neale RE, Abeni D, et al. Multicenter Study of the Association between Betapapillomavirus Infection and Cutaneous Squamous Cell Carcinoma. Cancer Res 2010; 70: 9777-86. 5. Bouwes Bavinck JN, Vermeer BJ, van der Woude FJ, et al. Relation between skin cancer and HLA antigens in renal-transplant recipients. N Engl J Med 1991; 325: 843-8. 6. Bouwes Bavinck JN, Tieben LM, van der Woude FJ, et al. Prevention of skin cancer and reduction of keratotic skin lesions during acitretin therapy in renal transplant recipients: a double-blind, placebo-controlled study. J Clin Oncol 1995; 13: 1933-8. 7. Stout GJ, Westdijk D, Calkhoven DM, et al. Epidermal transit of replication-arrested, undifferentiated keratinocytes in UV-exposed XPC mice: an alternative to in situ apoptosis. Proc Natl Acad Sci U S A 2005; 102: 18980-5. 8. Rebel HG, Bodmann CA, van de Glind GC, de Gruijl FR. UV-induced ablation of the epidermal basal layer including p53-mutant clones resets UV carcinogenesis showing squamous cell carcinomas to originate from interfollicular epidermis. Carcinogenesis 2012; 33: 714-20. 9. Voskamp P, Bodmann CA, Rebel HG, et al. Rapamycin impairs UV induction of mutant-p53 overexpressing cell clusters without affecting tumor onset. Int J Cancer 2012; 131: 1267-76. 10. Nijhof JG, Braun KM, Giangreco A, et al. The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development 2006; 133: 3027-37. 91 Multiple squamous cell carcinomas in a renal transplant patient. BWEADVSMGFINCORR:Opmaak 1 21-07-2014 17:40 Pagina 91

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