Please activate JavaScript!
Please install Adobe Flash Player, click here for download
ePaper created 2014-09-15, 12:31:02 | version 1.32.01
6. Fernandez-Rivas M, Bolhaar S, Gonzalez-Mancebo E, et al. Apple allergy across Europe: how allergen sensitization profiles determine the clinical expression of allergies to plant foods. J Allergy Clin Immunol 2006; 118: 481-8. 7. Le TM, Bublin M, Breiteneder H, et al. Kiwifruit allergy across Europe: Clinical manifestation and IgE recognition patterns to kiwifruit allergens. J Allergy Clin Immunol 2013; 131: 164-71. 8. Klemans RJ, Otte D, Knol M, et al. The diagnostic value of specific IgE to Ara h 2 to predict peanut allergy in children is comparable to a validated and updated diagnostic prediction model. J Allergy Clin Immunol 2013; 131: 157-63. 9. Masthoff LJ, Mattsson L, Zuidmeer-Jongejan L, et al. Sensitization to Cor a 9 and Cor a 14 is highly specific for a hazelnut allergy with objective symptoms in Dutch children and adults. J Allergy Clin Immunol 2013; 132: 393-9. Photodermatology The Department of Dermatology in Utrecht has a long tradition in research on photodermatology. The first professor in dermatology, van Leeuwen, accepted his chair with a speech entitled: “On the influence of sunlight on healthy and disesased skin”. He used light for the treatment of certain skin diseases. His successor, Zoon, studied patients with xeroderma pigmentosum. Rottier received the Finsen medal for photobiology in 1960 “for fundamental studies of the basic phenomena underlying the formation of erythema of the human skin by UV radiation”. In 1972 Van der Leun became head of the department of physics in dermatology. The phenomenon of light-induced tolerance to light was detected and developed for the treatment of several photodermatoses. Since 1974 it has become clear that the depletion of the ozon layer may be dangerous and could lead to an increase of skin cancer. Van der Leun became more and more involved in this area and was awarded the 1996 Finsen medal for photobiology for his contributions on this subject.[1] Huib van Weelden focused on the clinical aspects of photodermatology, more particularly on normal and abnormal reactions to light and the application of phototherapy for several skin diseases.[2,3] He also studied the risks of photocarcinogenesis in relation to the use of sun tanning beds. In 1988 he introduced the small spectrum UVB lamp (TL-01), nowadays the preferred treatment in phototherapy worldwide over PUVA and broad band UVB.[4] Furthermore, he investigated several photodermato- ses: polymorphous light eruption, actinic reticuloid, lupus erythematosus and erythropoietic protopor- phyria.[5-8] The treatment with light of several (skin) disorders, such as atopic dermatitis, psoriasis, acne and the Crigler-Najjar syndrome, also came under his attention. 75 Severe chronic actinic dermatitis in elderly male patient. BWEADVSMGFINCORR:Opmaak 1 21-07-2014 17:40 Pagina 75