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ePaper created 2014-09-15, 12:31:02 | version 1.32.01
Pediatric Dermatology From 1983 onwards J. Henk Sillevis Smitt was responsible for pediatric dermatology (PD) at the Academic Medical Center (AMC) and the outpatient clinic PD of the Emma Children Hospital which joined the AMC. The number of out-patient clinics in PD grew from one clinic a week in 1986 to 7 in 2014 including one at the Free University Amsterdam and day-care facilities for children. A second pediatric dermatologist, Pina M.A. Middelkamp Hup was appointed in 2008. Research is concentrated on immunology and allergology (primary immunodeficiencies or PID, atopic dermatitis), genodermatoses, and congenital/neonatal vascular lesions. In cooperation with the pediatric immunologists of the department of pediatrics and Sanquin Blood Supply, skin problems in PIDs were analyzed. It was shown that 31% of 16 X-linked Chronic Granulomatous Disease (CGD) carriers as well as two autosomal recessive patients with CGD displayed discoid lupus erythematosus-like lesions.[1,2] The histopathology was not typical and the immunofluorescence findings were negative, but the immunophenotype of the infiltrating cells resembled that found in discoid lupus erythematosus. A review of skin symptoms in PIDs helps the dermatologists to be aware of skin problems in immunodeficient children.[3] 42 Restrictive dermopathy in a newborn, a rare genodermatosis. BWEADVSMGFINCORR:Opmaak 1 21-07-2014 17:39 Pagina 42